Effects of light stress on the expression of Kisspeptin/GnRH in rat hypothalamus
نویسندگان
چکیده
Objective: This study aims to explore the effects of light stress on the expression of Kisspeptin/GnRH in rat hypothalamus. Methods: The rat model of chronic stress was established through artificial illumination time. The rats were divided into control group, continuous light group, interval light group and reverse day and night group randomly. The expression levels of Kisspeptin and GnRH in rat hypothalamus were detected by RT-PCR, westernblotting and immunohistochemical methods. Results: The results showed that the expression levels of Kisspeptin and GnRH in rat hypothalamus significantly decreased in continuous light group and reverse day and night group (P<0.05), there was no difference between interval light group and control group (P>0.05). Conclusions: Long time light stress can decrease the expression levels of Kisspeptin and GnRH in rat hypothalamus.
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